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Jin-A Lee

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I'm a Post-Doctoral Research Fellow in Professor Amy Wong's lab at the Hospital for Sick Children/University of Toronto. I am interested in finding a CFTR mutant-independent therapy for CF patients using hPSC and CF hiPSCs. In current research I am using CRISPR to generate a TMEM16A reporter line and enhance TMEM16A expression to study the role of TMEM16A in lung epithelial differentiation (2020 Medicine by Design New Ideas Awards).

I completed my PhD at Sungkyunkwan University in August 2019, where I was supervised by Professor Kyeong Kyu Kim, head of the Laboratory of Structural Biology in the Samsung Biomedical Research Institute and Sungkyunkwan University School of Medicine.

Publications

Selected publications, see my Google Scholar profile for more details.

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Gene therapy for cystic fibrosis: new tools for precision medicine.

Jin-A Lee, Alex Cho, Elena N. Huang, Yiming Xu, Henry Quach, Jim Hu, Amy P. Wong

Journal of Translational Medicine, Volume 19 (452),
Oct. 30, 2021

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A Developmental Role of the Cystic Fibrosis Transmembrane Conductance Regulator in Cystic Fibrosis Lung Disease Pathogenesis.

Elena N. Huang, Henry Quach, Jin-A Lee, Joshua Dierolf, Theo J. Moraes, Amy P. Wong

Frontiers in Cell and Developmental Biology, Volume 9 (742891)
Oct. 11, 2021

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Targeted epigenetic modulation using a DNA‐based histone deacetylase inhibitor enhances cardiomyogenesis in mouse embryonic stem cells.

Jin‐A Lee, Jieun An, Junichi Taniguchi, Gengo Kashiwazaki, Ganesh N. Pandian, Nazia Parveen, Tong Mook Kang, Hiroshi Sugiyama, Debojyoti De, Kyeong Kyu Kim

Journal of Cellular Physiology: 1–17
Oct. 23, 2020

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New screening system using Twist1 promoter activity identifies dihydrorotenone as a potent drug targeting cancer-associated fibroblasts.

Eunmyong Lee, So-Young Yeo, Keun-Woo Lee, Jin A. Lee, Kyeong Kyu Kim, Seok-Hyung Kim

Scientific Reports, Volume 10 (7058),
Apr. 27, 2020

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Discovery of Natural Compounds Promoting Cardiomyocyte Differentiation.

Jin-A Lee, Jieun An, Tong Mook Kang, Debojyoti De, Kyeong Kyu Kim

Stem Cells and Development, Volume: 28 (1)
Jan. 2, 2019

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Composition comprising Ursinoic acid derivatives for inducing the differentiation of stem cell and uses thereof

Kyeong Kyu Kim, Jin-A Lee, Debojyoti De

Korean Patent #101669368
October 25, 2016

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Composition comprising Lupinine derivatives for inducing the differentiation of stem cell and uses thereof

Kyeong Kyu Kim, Jin-A Lee, Debojyoti De

Korean Patent #101669367,
October 25, 2016

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Characterization of the Caenorhabditis elegans HIM-6/BLM Helicase: Unwinding Recombination Intermediates

*Hana Jung, *Jin-A Lee (*equal contribution), Seoyoon Choi, Hyunwoo Lee, Byungchan Ahn

PLOS ONE, Volume 9, Issue 7,
July 18, 2014

Curriculum Vitae/Resume

PDF Resume

Contact Me

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You can also find out more about me through one of the links below.